A win for the Young Bees would see them leapfrog their Hertfordshire rivals and could see them climb as high as fourth.
They currently sit 8th in the EFL Youth Alliance South East division, but are just 5 points off of 2nd.
Last time out, the Bees were 3-2 winners at home to Southend United at The Hive thanks to goals from Arale Mohammed, Rio Connell and Greg Adinna.
Kick off at Shephalbury Sports Academy (SG2 8NP) is at 10:30am.